Avène Cleanance Comedomed Anti-Blemish Concentrate has shown proven clinical effectiveness from seven days*, fights the appearance of spots from the root and prevents them from reappearing.

Expert care for oily, acne-prone skin, Avène Cleanance Comedomed Anti-Blemish Concentrate is formulated using Comedoclastin™, a plant extract from the seeds of Milk thistle. This active ingredient with patented properties** directly targets micro-imperfections, reduces the appearance of existing spots and blackheads, limits new ones from appearing, and removes excess sebum.

Avène Cleanance Comedomed Anti-Blemish Concentrate is suitable for adults and teenagers from the age of 12, applied twice a day, morning and evening, and offers clinically-proven*** anti-recurrence action. Non-comedogenic, high-tolerance* for acne-prone skin, its fast-absorbing, non-greasy texture leaves skin mattified.

Effective: on all types of blemishes on acne-prone skin, thanks to Comedoclastin™**, which acts at the root of imperfections to reduce them and limit their appearance.
Fast: reduces the appearance of spots in as little as seven days*. Prevents recurrence of imperfections***. For clearer skin and improved comfort every day.
Very Well Tolerated: used alone or in combination with drug treatments (excluding oral isotretinoin), its tolerance on sensitive, acne-prone skin is clinically proven*.

*Tolerance and efficacy study under dermatological control on 51 subjects, use of Avène Cleanance Comedomed Anti-Blemish Concentrate twice a day for 56 days.

**Patent registered.

***International clinical observational study, 90% of patients without acne relapse at T6 months, (according to the definition of relapse in the GEA protocol ≥3 requiring the introduction of a drug treatment – oral or local), 48 subjects, two applications per day of Avène Cleanance Comedomed Anti-Blemish Concentrate for six months.

Size: 30 mL

Cleanance Comedomed Anti-Blemish Concentrate Ingredients: Consumers are advised to check product composition systematically before purchasing.

AVENE THERMAL SPRING WATER (AVENE AQUA). WATER (AQUA). ZINC COCETH SULFATE. LAURYL BETAINE.DECYL GLUCOSIDE. CETEARETH-60 MYRISTYL GLYCOL. PEG-7 GLYCERYL COCOATE.POLYSORBATE 20.CITRIC ACID FRAGRANCE (PARFUM).GREEN 5 (CI 61570).ISOPROPYL.ACOHOL.PEG-40 HYDROGENATED CASTOR OIL.PEG-6.PPG-26-BUTETH-26. SILYBUM.ARIANUM FRUIT EXTRACT.SODIUM BENZOATE.SODIUM CHLORIDE.SODIUM HYDROXIDE.TRISODIUM ETHYLENEDIAMINE DISUCCINATE.YELLOW 5 (CI 19140).ZINC GLUCONATE.